What is Sotyktu?
Sotyktu is the brand name for the oral systemic treatment deucravacitinib. Different oral systemic treatments work in different ways to reduce symptoms of psoriatic disease. Newer oral systemic treatments, such as Sotyktu, work similarly to biologics by targeting specific parts of the immune system to reduce symptoms and inflammation.
How Does Sotyktu Work?
Sotyktu is a selective, allosteric tyrosine kinase 2 (TYK2) inhibitor. TYK2 is a member of the Janus Kinase (JAK) family. This means it targets a specific part of the immune system (TYK2) to reduce the overactive immune response associated with psoriasis.
How Is It Used?
Sotyktu is taken once daily by mouth.
What Are the Common Side Effects?
Common side effects may include:
- Upper respiratory tract infection
- Increase in blood creatine phosphokinase levels
- Herpes simplex
- Mouth ulcers
- Inflamed hair pores (folliculitis)
- Acne
