Psoriasis Forum Journal
Psoriasis Forum, a peer review journal, published quarterly by the National Psoriasis Foundation, Psoriasis Forum is the only publication of its kind—dedicated to providing up-to-date and practical information to health care providers on the front line of psoriasis and psoriatic arthritis treatment.
Psoriasis Forum is sent to professional members of the Psoriasis Foundation.
Current issue: Fall 2014 Vol. 20, No. 3
Treatment of Refractory Psoriasis with Ustekinumab in an HIV -Positive Patient: A Case Presentation and Review of the Biologic Literature
Shira Wieder, B.A., Ethan Routt, B.A., Jacob Levitt, M.D., Mark Lebwohl, M.D.
Here we describe a case of a 39-year-old male with HIV and a 20-year history of generalized plaque psoriasis and psoriatic arthritis. The patient had been refractory to all treatments until initiating ustekinumab, the monoclonal antibody against IL-12/23. While using ustekinumab, the patient’s CD4 T-cell count and HIV viral load have remained stable. Due to the questions surrounding the use of biologics in HIV-positive patients, we review the successful use of anti-TNF agents in patients with chronic HIV infection as well as the single other reported case of ustekinumab’s use in an HIV-positive patient. We therefore begin to build the case for ustekinumab as an alternative biologic therapy for the HIV-infected psoriasis patient.
Also in this issue:
- Safety and Efficacy of Cyclosporine in Psoriatic Arthritis
- Tonsillectomy and Antistreptococcal Interventions for Psoriasis: A Review
- Influence of Cutaneous Involvement in Deciding How to Treat Psoriatic Arthritis
Online access to current and past issues of Psoriasis Forum is available to professional members.