National Psoriasis Foundation

Health Conditions Associated with Psoriasis

Individuals with psoriasis are at an elevated risk to develop other chronic and serious health conditions also known as "comorbidities." It is estimated that up to 30 percent of people with psoriasis develop psoriatic arthritis. People with psoriatic disease also are at greater risk of developing cardiovascular disease and depression.

Psoriatic Arthritis

Up to 30 percent of people with psoriasis also develop psoriatic arthritis, which causes pain, stiffness and swelling in and around the joints and tendons. Learn more about types, symptoms, and treatments for psoriatic arthritis »

Cardiovascular Disease

Research continues to link psoriasis with an increased risk for cardiovascular disease, especially in people with severe psoriasis. People with severe psoriasis are 58 percent more likely to have a major cardiac event and 43 percent more likely to have a stroke. National Psoriasis Foundation has supported research examining the link between the two diseases. Learn more about the connection »


People with psoriasis are at an increased risk for type 2 diabetes, according to a 2012 study. People with severe psoriasis are 46 percent more likely to have type 2 diabetes. Learn more about the connection between psoriasis and diabetes »


Psoriasis can cause considerable emotional distress for people, including decreased self-esteem, and an increased incidence of mood disorders, such as depression. One study estimates that approximately one-fourth of people with psoriasis have depression. Studies show that treating your psoriasis can alleviate symptoms of depression.

Other Conditions

Other comorbidities associated with psoriasis include cancer, obesity, metabolic syndrome and other immune-related conditions such as Crohn's disease. A number of studies have found that people with psoriasis have an increased risk of certain types of cancer, such as a form of skin cancer known as squamous cell carcinoma and lymphoma. In some instances, these cancers have been associated with specific psoriasis treatments which suppress the immune system. Patients should follow recommended regular health screenings for cancer and avoid high risk behaviors.